Applied Photophysics - For Circular Dichroism and Stopped-flow Spectroscopy
 

Get more from your protein

Chirascan™-plus Dynamic Multi-mode Spectroscopy (DMS)

Chirascan-plus circular dichroism spectromter

Information-rich, label-free, sample efficient and fast.

Chirascan-plus DMS will:

  • Prove that a protein is initially correctly folded and hence biologically active
  • Distinguish between unfolding and aggregation steps, which is of relevance to immunogenicity
  • Identify the structural components that change and the order in which they denature, giving valuable information on conformation
  • Determine quantitatively the Tm and van't Hoff enthalpy values as indicators of stability

Read our case study:Testing the stability of antibody biotherapeutics in different formulations using dynamic multi-mode spectroscopy (DMS)

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