Integrative Structural Biology 2023



3rd Integrative Structural Biology meeting in Marseille

The 3rd edition of the Integrative Structural Biology Meeting (BSI)is co-organized with the Association Française de Cristallographie (AFC) and the Société Française de Biophysique (SFB). Their local committee involves 13 laboratories and institutes of Aix-Marseille Université. It is working hard to propose exceptional scientific sessions to cover a wide range of scientific research in the fields of Biophysics, Structural Biology, and Cell Biology.

We will celebrate the 40th anniversary of the Société Française de Biophysique (SFB), and the RECIPROCS network will organize a half-day satellite meeting available to all participants. BSI are committed to achieving gender equality, inclusiveness, and diversity in their endeavours, and they strongly encourage the participation of graduate students and young scientists.

We are in the midst of a historic and profound technical transformation of structural and cellular biology. The development of techniques based on super-resolutionptical microscopy and cryo-electron microscopy break down resolution barriers for understanding the architecture of proteins, organelles, cells and tissues, with the potential for a holistic understanding of biological processes with multi-scale structural approaches. As a result, communities of structural biologists, biophysicists, biochemists, and cell biologists are more interconnected than ever. Sharing our expertise and innovations will allow us to see biology in all its dimensions and better understand its diverse mechanisms.

The program

The 3rd BSI meeting is comprised of 10 scientific sessions with 4 keynotes and 11 invited talks given by experts in the fields of viruses, microbes, machine learning, cell biology, drug design, cancer, neurons, methods, and plants.

Each session will feature invited contributions and talks selected from abstract submissions. Three poster sessions will give ample opportunity to discover new research. Poster prizes will be awarded on Friday.

A gala dinner will be held on Wednesday, Nov 15th, at the MOLE PASSEDAT restaurant at the MUCEM.


Keynote speakers 

Jessica Andreani

CEA, Paris-Saclay, France - Jessica Andreani is a CEA researcher in computational biology and bioinformatics at the Institute for Integrative Biology of the Cell (Paris-Saclay, France). Her research focuses on the structural prediction of macromolecular assemblies, in particular protein-protein and protein-nucleic acid interactions. To this end, her methodological interests include the integration of diverse sources of information, such as evolutionary and omics data, as well as deep learning approaches.

Enrica Bordignon

Ruhr University of Bochum, Bochum Germany - Enrica Bordignon is an expert in EPR Spectroscopy applied to membrane proteins. In 2000 she obtained a PhD in Chemistry at the University of Padova (Italy), then moved as post doc in the group of Prof. Steinhoff at the University of Osnabrück (Germany) and later to ETH Zurich in the group of Prof. Jeschke as senior post doc. In 2013 she became professor for biophysics at the FU Berlin and since 2016 she leads the EPR group at the Ruhr University Bochum. She investigates with site-directed spin labeling EPR the dynamics and conformational changes of membrane proteins, and in particular of apoptotic proteins and ABC transporters. Together with her collaborator Prof. Seeger (University of Zurich), she pioneered the use of spin-labeled nanobodies as conformational reporters of membrane proteins in cells (Galazzo et al., PNAS 2020).



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