Chirascan™ V100

Ready to run –

when sensitivity and accuracy are key

Suitable for studying chiral molecules of all types and sizes, the sensitivity and accuracy of a Chirascan V100 CD spectrometer ensure that researchers get the most from every CD analysis, generating high quality data that contribute to a deeper understanding of biomolecular characteristics, mechanisms and interactions.

More than α-helix and β-sheet -
determine structural and thermodynamic properties

  • Achieve highest sensitivity and accuracy
  • Gain insight and detect changes in secondary and tertiary structure
  • Determine response to thermal or chemical change
  • Study folding and unfolding mechanisms
  • Expand capabilities with dedicated Chirascan accessories
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Ready to run

Chirascan systems are supplied with the features and accessories required for acquisition of high quality data from ‘day one’.

MOLECULAR SIEVE,
ACTIVATED CHARCOAL FILTER

  • Removes common gas impurities

ACTIVE NITROGEN
MANAGEMENT SYSTEM

  • Regulates purge gas consumption
  • Software-controlled

AIR-COOLED XENON LAMP

  • Software-controlled
  • Up-time recorded

MONOCHROMATOR

  • Produces horizontally, linearly polarized ­monochromatic light
  • Dual polarizing prisms maximize light ­throughput

PHOTOELASTIC MODULATOR

  • Converts horizontally polarized light to ­circularly polarized light. ­Alternates between left- and right-handed circular polarized light

TEMPERATURE-CONTROLLED
SAMPLE CHAMBER

  • Consistent analytical conditions
  • Continuous temperature ramps
  • Temperature measured directly in sample

WATER CIRCULATOR

  • Dissipates heat from sample chamber and sample storage Peltiers

AVALANCHE PHOTODIODE DETECTOR

  • Highest sensitivity (high signal: noise)

OPTICS-BASED, MULTIWAVE­LENGTH CALIBRATION

  • For CD accuracy

CUVETTES AND HOLDERS

  • Selected for far- and near-UV CD analysis of biomolecules (single sample mode)
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Control and analysis software

  • Easily defined run parameters and store routine protocols
  • Saves time with scheduled start-up/shutdown of lamp and N2 supply
  • Fail-safe lamp switch-off if N2 flow drops
  • Ensures O2-free conditions with N2 purge
  • Recognizes flow cell to select optimal run/wash/dry protocol

GLOBAL THERMODYNAMIC ANALYSIS

  • Derive melting points and enthalpies from multiwavelength, thermal ­denaturation ­experiments
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