Optimising Circular Dichroism Measurements

One of the most common questions users new to Circular Dichroism spectroscopy ask is how much sample they need—and how little they can get away with.

Generally, the simple answer is: it depends. There are a couple of different experimental conditions and constraints that affect sample requirements, and a number of interdependent parameters.

Use the interactive demo below to gain a better understanding of what the most critical aspects are of optimising CD measurements.

*For best results, use on a desktop/laptop screen

Note that this applet is greatly simplified and goes without claim to provide accurate quantitative results.

Related:

circular dichroism FAQs

Applet created with permission using GeoGebra.

Applet may work slower for some users based on their internet speed.