Metal Ion-Induced Hydrogel Formation

Followed by far-UV CD spectroscopy

A Chirascan case study.

Selegard Et Al Graphs Textpaths

In this study, the folding driven self-assembly of a peptide-hyaluronan hybrid hydrogel was followed by far-UV CD Spectroscopy.

Addition of zinc ions triggered folding of the peptides into a helix-loop-helix motif and dimerization into four-helix bundles, resulting in hydrogelation of the hybrid polymer.

See the original paper here:

Selegård et al. 2017, Sci. Rep. 7:7013

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Have a look at the system that was used in this study.