From structural characterization with Chirascan, to stability screening with SUPR-DSF, and kinetic analysis with the SX20, our systems deliver the data you need to design and optimize bispecifics with confidence.
16th World Bispecific Summit
9th - 11th September 2025
Join Nicoya and Applied Photophysics at the 16th World Bispecific Summit!
The 16th World Bispecific Summit returns as the industry’s longest-running and most comprehensive event, devoted exclusively to the design, development, and translation of bispecific and multispecific therapeutics. Bringing together the industry leaders, making it all happen, including Regeneron, Sanofi, Novartis, Immunocore, Zymeworks, and more to share actionable insights and real-world case studies. Attendees will gain strategies to design more effective bispecifics, select smarter target pairings, streamline manufacturability, and mitigate safety risks - accelerating the path from discovery to clinic.
Join Nicoya and Applied Photophysics at the World Bispecific Summit to explore how SPR, circular dichroism, stopped-flow kinetics, and protein stability screening are advancing the design, characterization, and developability of bispecific antibodies.
Agenda
Day One
8:00 am Morning Coffee and Check-in
8:55 am Chair’s Opening Remarks
9:00 am Creating Conditionally Acting, Multifunctional Cell Engagers with Enhanced Target Selectivity & Reduced Toxicity Potential
9:30 am Session Reserved for Invenra
10:00 am Morning Break & Speed Networking
11:00 am Exploring a Novel Mechanism of Action With the Development of TCR-PD1 Agonist Bispecifics For The Treatment of Autoimmune Diseases
11:30 am Session Reserved for Alloy Therapeutics
12:00 pm Lunch
1:00 pm ZW1528: A Dual-Targeting Bispecific Antibody to Broadly Suppress Airway Inflammation by Inhibiting IL-4Ra and IL-33 Pathways
1:30 pm Conditionally active 41BB Costimulatory CD19 x CD20 T Cell engager designed for deeper and durable responses and minimal cytokine release for Autoimmune Diseases
2:15 pm Afternoon Break & Poster Session
2:45 pm Session Reserved for Alloy Therapeutics
3:15 pm Panel Discussion: Strategic Target Selection for Optimizing Bispecific Design & Function
4:15 pm Session Reserved for BSP Pharmaceuticals
4:30 pm Chair’s Closing Remarks
4:45 pm End of Conference Day One
Day Two
8:00 am Morning Coffee & Check-in
8:55 am Chair’s Opening Remarks
9:00 am Supercharging T Cell Engagers: Expanding Immune Activation Beyond Traditional Bispecific Design
9:30 am Beyond Bispecifics: Tetraspecific T Cell Engagers to Enhance T Cell Activation & Overcome Tumor Heterogeneity & Antigen Loss
10:00 am Conditionally Active CD2 Co-Stimulatory DLL3 T-Cell Engager With Increased Efficacy & Minimal Cytokin Release Compared to TarlatamabTM in Small Cell Lung Cancer & Neuroendocrine Tumors
10:30 am Morning break
11:00 am Companion T Cell Engagers for Covalent Inhibitors of Oncoproteins Blend Targeted & Immune Therapy to Overcome Cancer Cell Resistance
11:30 am Engineering Bispecific & Bipartopic ADCs for Dual-Target Engagement: Overcoming Design Challenges
12:00 pm Lunch Break
1:00 pm From Bispecifics to Tetraspecifics: Multiple Targets, One Drug
1:30 pm Exploring Masking Technology to Enhance Specificity & Cytotoxic Activity of Bispecifics
2:00 pm Roundtable Discussion: Bridging Biology & Translation: Optimizing Bispecific Design Through Cross-Continuum Insight
3:00 pm Chair’s Closing Remarks
3:15 pm End of Conference Day Two
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