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Protein Sciences In Drug Discovery
18th-19th November 2024, Cambridgeshire, England
Suitable for studying chiral molecules of all types and sizes, the sensitivity and accuracy of a Chirascan V100 circular dichroism spectrometer ensure that researchers get the most from every CD analysis, generating high-quality data that contribute to a deeper understanding of biomolecular characteristics, mechanisms, and interactions.
More than α-helix and β-sheet—determine structural and thermodynamic properties
Increased sensitivity when sample is limited
Since their introduction in 2005, Chirascan™ systems have continued to feature in thousands of peer-reviewed publications covering a wide range of research areas. The Chirascan V100 now offers the increased sensitivity and accuracy preferred for CD analysis of biomolecules.
Conventional chemical calibration methods require considerable skill in preparation. Standards, such as camphor-10-sulfonic acid (CSA), are unstable, photolabile, and hygroscopic. In addition, single-wavelength calibration (290.5 nm) assumes the same linear response at all wavelengths.
The optics-based, multiwavelength calibration method used for Chirascan V100 and Chirascan Q100 systems overcomes these challenges. The correct calibration is applied to every wavelength to yield accurate CD values.
Chirascan systems are supplied with the features and accessories required for acquisition of high quality data from ‘day one’.
Dr Dan Pantos, a Senior Lecturer and Head of Organic Chemistry at the University of Bath, utilises the Chirascan CD instrument from Applied Photophysics for various research projects. His primary research involves studying the interactions between chiral small molecules and quadruplex DNA, with the goal of developing anti-cancer treatments.
Dr Tonya Zeczycki, an associate professor at the Brody School of Medicine at ECU, studies Alzheimer's, Parkinson's, and other neurodegenerative diseases in her lab. She focuses on protein interactions, misfolding, and aggregation.
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18th-19th November 2024, Cambridgeshire, England
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15th – 17th October 2024, Basel, Switzerland
Applied Photophysics is a company with a prestigious legacy and has been supporting scientists for over 50 years.